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To date, a clear link between the use of the drug and a majority of those side effects has not been firmly established.
Three studies were designed to evaluate the effects of orlistat compared to placebo in reducing weight regain after a previous weight loss achieved following either diet alone (one study, 14302) or prior treatment with orlistat (two studies, 14119C and 14185).
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However, people should not take Alli if they're allergic to orlistat, have chronic malabsorption syndrome (are not able to absorb food and nutrients appropriately), or have a gallbladder condition.
Public Citizen welcomes the announcement by the Food and Drug Administration (FDA) that the agency has approved a new black box warning for the antibiotic tigecycline (brand name: Tygacil).
TID) was introduced in the United States in 1999 following rigorous clinical studies and FDA approval.
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Public Citizen urges the Centers for Medicare and Medicaid Services to withdraw coverage for the Wingspan Stent System and similar systems, because new data reveals that these systems provide no benefits and dramatically increase the risk of stroke or death.
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The reviewed studies found that weight-loss maintenance treatment with orlistat or sibutramine and dietary modification, supplementing caffeine or protein, following a lower-fat diet, adherence to physical activity, continued participant contact, problem-solving therapy, and the alternative treatment acupressure were effective in reducing weight regain after weight-loss treatment.
The 60-mg dose is better tolerated than the 120-mg dose and the gastrointestinal side effects are less when people taking the drug also eat less than 30% of their total calories from fat.
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Thus, psychological treatments for BED likely prevent the upward weight trajectories of individuals with BED.
The Food and Drug Administration (FDA) today recklessly approved another diet drug, lorcaserin, the latest in a series of obesity-related pharmaceuticals that pose serious health threats.
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The problem-solving therapy group meetings did not include didactic material but centered on therapist-led group discussions about solutions to participant-introduced weight management issues.
Animal data: Seven rodent studies submitted to the FDA for orlistat showed a dose-related increase in colonic cell proliferation (see Table 2).
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Public Citizen strongly oppose Food and Drug Administration (FDA) approval of over-the-counter (OTC) montelukast because, relative to existing FDA-approved OTC products for allergic rhinitis, the drug: (1) offers marginal clinical benefit relative to placebo and generally appears to have inferior effectiveness compared to existing FDA-approved OTC allergy products and (2) poses significantly greater risk, both to patients who meet the proposed indication and to those likely to use the drug for off-label indications.
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